 | Acta Crystallographica Section F Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS |
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![[Figure 2]](nw5071fig2mag.jpg)
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Figure 2
(a) Overall structure of PCNA with bound APIM. PCNA is shown in ribbon representation and the subunits in the PCNA trimer are shown in green, cyan and magenta. The IDCL (Leu118–Tyr133) of each PCNA subunit is shown as a thick tube coloured in blue. APIMs bound to the PCNA subunits are shown in stick representation (yellow, pink and grey). (b) Stereoview of the electron density of the APIM peptide boxed in (a) as a representative (weighted 2Fo − Fc map contoured at 1.0σ). (c) Binding of APIM to PCNA. Left: the molecular surface of PCNA is shown in cyan and the IDCL is highlighted in blue. APIM is shown as a yellow tube. The side chains of all residues are shown in stick representation. Right: the electrostatic potential of PCNA is mapped onto the molecular surface. Blue and red surfaces indicate positive and negative potentials, respectively. (d) Binding of the canonical PIPM of p21 to PCNA. The structure of p21 bound to PCNA is shown as a silver tube (PDB entry 1axc; Gulbis et al., 1996  ). Consensus residues in PIPM are shown in stick representation and are labelled. PCNA is shown as a surface representation as in the left panel of (c). |
![[Figure 2]](nw5071fig2.jpg)
| STRUCTURAL BIOLOGY COMMUNICATIONS |
ISSN: 2053-230X
