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Figure 2
(a) The active site of native neprilysin, with zinc represented as a silver sphere coordinated to His584, His588, Glu647 and phosphate ion. (b) Active site of neprilysin bound to phosphoramidon. The His584, His588 and Glu647 coordinations of Zn2+ are omitted for clarity. (c) Active site of the thiorphan complex. Ligand-omit FoFc density maps are contoured at 3σ (green).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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