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Figure 1
Crystal structure of an SFPQ homodimer in space group C2221. (a) Domain architecture of SFPQ. (b) Stereoview of the crystal structure of SFPQ in space group C2221 in cartoon representation. Residues modeled in the final structure are colored gold (RRM1), dark blue (RRM2), orange (NOPS) and red (coiled coil). The construct boundary used in this study is indicated with a square box and includes residues 276–535 of SFPQ. (c) Stereoview of the SFPQ dimer with the other monomer (gray) generated by the symmetry operation (−x − 1, y, −z − 1/2). |