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Figure 1
Crystal structure of the S. pombe Ubc7–U7BR complex. (a) Structure-based alignment of S. pombe U7BR, H. sapiens G2BR and S. cerevisiae U7BR. Residues within helices are represented by cylinders above the alignment. Residues that interact with Ubc7 are labeled with red or black circles. (b) S. pombe Ubc7 shown as a green cartoon and surface with U7BR represented as a cyan ribbon. Cys90 of Ubc7 is shown as sticks and spheres, and the N- and C-termini of U7BR are labeled. Below, similar structures of the E2BRs of H. sapiens (purple; PDB entry 3h8k; Das et al., 2009BB8) and S. cerevisiae (orange; PDB entry 4jqu) superimposed. Figures were made with PyMOL (v.2.0; Schrödinger).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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