Figure 3
Conserved E2-interacting residues among ERAD E2BRs. (a) A conserved E2BR lysine may form a hydrogen bond to a Ubc7 side chain in S. pombe (cyan), H. sapiens (purple) and S. cerevisiae (orange). (b) A conserved alanine and arginine interact with residues of Ubc7 in S. pombe (cyan), H. sapiens (purple) and S. cerevisiae (orange). |