|
Figure 4
Molecular packing of EcDSCD in three different crystal forms. (a) In space group P3121 (PDB entry 1c4t), the trimer (in red) cannot form the 24-mer biological assembly. The dimensions of the unit cell (blue lines) shown in the plane are a = b = 112.18 Å. (b) In space group F432 (PDB entry 1scz), the packing forms a 24-mer biological assembly (in red). The dimensions of the unit cell (blue lines) shown in the plane are a = b = 220.58 Å. (c) In space group I4 (PDB entry 6pbr, this work), the packing shows a 24-mer biological assembly (in red). The dimensions of the unit cell (red lines) shown in the plane are a = b = 128.60 Å. The building block for all of the crystal forms of EcDSCD is a trimer [shown in red in the P3121 (d), F432 (e) and I4 (f) crystal forms]. Intermolecular interactions between the trimers are unique in the different crystal forms, as shown, while the monomer/trimer itself shows a minimal conformational change between crystal forms [Figs. 3 ![]() ![]() |
Open
access
![Open Access](/logos/open.png)