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Figure 1
The two bacterial biosynthetic pathways to branched α-glucan (glycogen). (a) The well known GlgA-dependent pathway uses ADP-glucose (ADPG) as the building block for the polymerase (for example in E. coli). (b) The configuration of the pathway in M. tuberculosis, which lacks GlgA. The recently discovered GlgE pathway uses α-maltose-1-phosphate (M1P) as the building block for the polymerase. One route to this building block is via GlgM (GT4), a homologue of GlgA (GT5). G6P, glucose-6-phosphate; G1P, glucose-1-phosphate; UDPG, UDP-glucose; T6P, trehalose-6-phosphate. The figure is adapted from Koliwer-Brandl et al. (2016BB17).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 76| Part 4| April 2020| Pages 175-181
https://doi.org/10.1107/S2053230X20004343
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