Figure 3
Crystal structure of the IRF4 DBD on ISRE DNA. The IRF4 DBD is in a B-factor putty cartoon representation, where the cartoon thickness and colour reflect the relative Cα B factors within the molecule. The ISRE DNA is coloured magenta. The σA-weighted 2Fo − Fc refined map is shown (grey mesh) at a contour level of 1.5σ. The map, focusing on one of the recognition helices, was carved around the atomic model of the IRF4 DBD with a border of 2 Å to improve clarity. This figure was prepared with PyMOL (version 2.0; Schrödinger). |