Figure 3
The preliminary structure of the SALM3–PTPσ complex. (a) Placement of the proteins. LRR and LRR′ denote the LRR domains of the SALM3 dimer; the PTPσ Ig1-3 domains are indicated and are visible on each side of the SALM3 dimer. A composite omit map at the 1σ contour level is displayed on the complex. (b) Alignment of the SALM3 complex (blue) with the monomeric SALM5 complex (dark red). For simplicity the whole 2:2 dimer is not shown here. |