Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor δ in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative

Oyama, T.; Takiguchi, K.; Miyachi, H.

doi:10.1107/S2053230X22000449

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

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Figure 1
(a) A schematic diagram of the ligand-activated PPARδ–RXRα heterodimer. (b) Chemical structures of the ligands used in this study. Functional units are shown on the KCL structure with the binding arms in the ligand-binding pocket of PPARδ.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 78| Part 2| February 2022| Pages 81-87

https://doi.org/10.1107/S2053230X22000449

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