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Figure 11
Active-site loop of human 6PGDH in the open (yellow) and closed (red) conformations from superimposition of the apoenzyme (light blue; PDB entry 4gwg) and the NADPH complex (magenta; PDB entry 2jkv), where the substrate-binding site is occupied by a sulfate and a chloride ion [reproduced from Haeussler et al. (2018BB39) with permission from Elsevier].

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 78| Part 3| March 2022| Pages 96-112
https://doi.org/10.1107/S2053230X22001091
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