Figure 8
Binding modes of NADPH (left; PDB entry 1pgo) and nicotinamide-8-bromoadenine dinucleotide phosphate (Nbr8ADP, an analogue of NADP+; right; PDB entry 1pgn) to ovine 6PGDH. One sulfate is present in the substrate-binding site on the left while a pyrophosphate is on the right, as indicated by arrows (created using PyMOL). |