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Figure 1
View of the sugar-binding site of concanavalin A studied by X-ray crystallography enlarged to view the two sugars superimposed. The smaller red spheres are the O atoms of bound water molecules. The H atoms are not displayed as these were not experimentally determined. The two crystal structures have been deposited in the Protein Data Bank as entries 1gic (the protein with glucoside) and 5cna (the protein with mannoside; Naismith et al., 1994BB14). The dashed lines are putative hydrogen bonds. The blue arrows point out the key difference between the mannoside and glucoside O2 atom orientations, i.e. the mannoside orientation is vertical. This figure was prepared using CCP4mg (McNicholas et al., 2011BB13).

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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