Figure 3
Biotransformation of acetophenone (11) and the fluorinated derivatives 13, 15 and 18 by AdRedAm in the presence of NADPH and methylamine (MeNH2) (n.r., not recorded; González-Martínez et al., 2020). Also shown is the hydrate 20 of 18 that is observed in the active site of the IRED from S. roseum (PDB entry 5ocm; Lenz et al., 2018). |