Figure 2
(a) Crystal structure of NG-FlhF. (b) Electron density reveals bound GDP. (c) A close-up view of the active site reveals the canonical GTPase motifs. (d) Superposition of our GDP-bound NG-FlhF (blue) with GTP/Mg2+-bound NG-FlhF (red). (e) A side-by-side view of the G2 and G3 loops reveals a tightening of the active site. (f) The N domain rotates during the transition between GDP-bound and GTP-bound states. |