Figure 3
Elbow angles for Fabs D08 (a), D08* (b), BLV5B8 (c) and BLV5B8* (d) presented in cartoon representation. Chains are coloured as in Fig. 1: the BLV5B8 HC is in white, the D08 HC is in black, the BLV5B8 LC is in magenta and the D08 LC is in red. Blue dumbbells indicate psuedo-dyad rotation axes of each immunoglobulin domain with calculated hinge residues highlighted as green spheres (LC) or red spheres (HC). Elbow angles (Stanfield et al., 2006) were visualized using the PyMOL Elbow Angle script (Sampson, 2014). |