The impact of exchanging the light and heavy chains on the structures of bovine ultralong antibodies

Clarke, J.D.; Douangamath, A.; Mikolajek, H.; Bonnet-Di Placido, M.; Ren, J.; Fry, E.E.; Stuart, D.I.; Hammond, J.A.; Owens, R.J.

doi:10.1107/S2053230X2400606X

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

IUCr IT WDC

home archive editors for authors for readers submit subscribe open access

view article

Figure 4
Molecular interactions supporting the ultralong stalk motif in ultralong Fabs (a, c) D08 and (b, d) D08* from side (a, b) and top-down (c, d) views. Complementarity-determining regions are coloured according to Fig. 1

; the D08 heavy chain is in black, the D08 light chain is in red and the BLV5B8 light chain is in magenta, with increasing saturation from CDR1 to CDR3. For clarity, the field of view is focused on the ultralong CDR3H stalk motifs and immediate residues. π-Stacking interactions between aromatics are represented with dashed lines.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 80| Part 7| July 2024| Pages 154-163

https://doi.org/10.1107/S2053230X2400606X

Open

access

Follow Acta Cryst. F

Search IUCr Journals		doi		Advanced search
Author		volume	page