 | Acta Crystallographica Section F Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS |
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![[Figure 3]](nw5126fig3mag.jpg)
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Figure 3
Comparison of enteroviral 3C proteases with reported structures. (a) Structural alignment of 3C proteases. 3C proteases from poliovirus (PV, cyan, PDB entry 1l1n; Mosimann et al., 1997  ), EV-B93 (orange, PDB entry 3q3x; Costenaro et al., 2011), EV-D68 (lemon, PDB entry 3zv8; Tan et al., 2013), CVA16 (slate, PDB entry 3sj8; Lu et al., 2011), HRV-C15 (yellow, PDB entry 6ku7; Yuan et al., 2020), EV-A71 (wheat, PDB entry 3osy; Cui et al., 2011), CVB3 (gray, this study) and CVB4 (magenta, this study) are included in the comparison. Alignments of these 3C proteases yield r.m.s.d. values that demonstrate the similarity between these enzymes. (b) Multiple-sequence alignment of 3C proteases from different enteroviruses. The MEGA software (version 10.2.5) was used to perform the alignment. The sequence-alignment visualization was generated using ESPript 3.0. (c) Structural alignment of the CVB3 (gray, this study), CVB4 (magenta, this study) and EV-B93 (orange, PDB entry 3q3x) 3C proteases. Obvious local differences are labeled with green lines or dashed boxes. (d) An enlarged view of reigions 1–3 with obvious local differences. (e) An enlarged view of the catalytic triad of 3C proteases. |
![[Figure 3]](nw5126fig3.jpg)
| STRUCTURAL BIOLOGY COMMUNICATIONS |
ISSN: 2053-230X
