Structure of Clostridium leptum carboxyspermidine decarboxylase and comparison to homologs prevalent within the human gut microbiome

Jones, S.J.; Bell, D.J.; McFarlane, J.S.

doi:10.1107/S2053230X25000482

Acta Crystallographica Section F
Acta Crystallographica
Section F STRUCTURAL BIOLOGY COMMUNICATIONS

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Figure 4
CASDC family comparison. (a) Dendrogram generated in DALI illustrating the structural relationships of CASDC enzymes from high-frequency human gut genera. Coloured blocks are for illustration and coordinate with the structural overlays. ClCASDC is displayed as a grey cartoon. (b) Alignment of Campylobacter jejuni CASDC. (c) Alignment of Ruminococcus flavefaciens CASDC. (d) Alignment of Akkermansia muciniphila CASDC. (e) Alignment of Helicobacter pylori CASD. The β6/β7 loop is indicated by brackets. The α9/β12 loop is indicated by circles.

STRUCTURAL BIOLOGY
COMMUNICATIONS

ISSN: 2053-230X

Volume 81| Part 3| March 2025|

https://doi.org/10.1107/S2053230X25000482

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