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accessThe first report of structural analysis of a nucleic acid using crystals grown in space. Corrigendum
aGraduate School of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan, and bDepartment of Materials and Life Sciences, Faculty of Science and Technology, Sophia University, 7-1 Kioi-cho, Chiyoda-ku, Tokyo 102-8554, Japan
*Correspondence e-mail: j.kondo@sophia.ac.jp
Corrections are made to the article by Ando et al. [(2025![[Ando, S., Takahashi, M. & Kondo, J. (2025). Acta Cryst. F81, 95-100.]](../../../../../../logos/arrows/f_arr.gif "Ando, S., Takahashi, M. & Kondo, J. (2025). Acta Cryst. F81, 95-100."){kind=small}
), Acta Cryst. F81, 95–100].
Keywords: X-ray crystallography; nucleic acids; microgravity.
In the Introduction of the article by Ando et al. (2025; page 96, lines 12–16 of the left column), we previously wrote:
To the best of our knowledge, there is only one report of nucleic acid crystallization in a microgravity environment, and the results did not have sufficient resolution to be used for structural analysis or investigation of the effects of gravity (Lorenz et al., 2000
However, we have realised that this statement was inaccurate. In fact, several significant studies have successfully achieved nucleic acid crystallization in microgravity environments, followed by structural determination.
The corrected sentence should read as follows:
Several studies have reported nucleic acid crystallization and subsequent in a microgravity environment (Lorenz et al., 2000
Additionally, at the end of the Introduction, we previously wrote:
In this study, we conducted the crystallization of a DNA/RNA heteroduplex in space and provide the first report on nucleic acid crystallization under microgravity and subsequent structure analyses.
However, this statement also contained an inaccuracy, as previous studies have reported RNA crystallization under microgravity and structural determination.
The corrected sentence should read as follows:
In this study, we conducted the crystallization of a DNA/RNA heteroduplex in space and present a report of systematic evaluation of nucleic acid crystallization under microgravity, providing new perspectives on how microgravity conditions may influence crystal quality and structural analyses.
We also acknowledge that the title of our paper may not fully reflect the historical context of microgravity nucleic acid crystallization studies, and we apologize for any confusion that may have arisen as a result.
This correction does not affect the overall conclusions of our study.
Funding information
This work was supported by the Research Support Project for Life Science and Drug Discovery [Basis for Supporting Innovative Drug Discovery and Life Science Research (BINDS)] from AMED under Grant Nos. JP22ama121014 and JP23ama121014.
References
Ando, S., Takahashi, M. & Kondo, J. (2025). Acta Cryst. F81, 95–100. CrossRef IUCr Journals Google Scholar
Lorenz, S., Perbandt, M., Lippmann, C., Moore, K., DeLucas, L. J., Betzel, C. & Erdmann, V. A. (2000). Acta Cryst. D56, 498–500. Web of Science CrossRef CAS IUCr Journals Google Scholar
Rypniewski, W., Vallazza, M., Perbandt, M., Klussmann, S., DeLucas, L. J., Betzel, C. & Erdmann, V. A. (2006). Acta Cryst. D62, 659–664. Web of Science CrossRef CAS IUCr Journals Google Scholar
Vallazza, M., Banumathi, S., Perbandt, M., Moore, K., DeLucas, L., Betzel, C. & Erdmann, V. A. (2002). Acta Cryst. D58, 1700–1703. Web of Science CrossRef CAS IUCr Journals Google Scholar
Vallazza, M., Perbandt, M., Klussmann, S., Rypniewski, W., Einspahr, H. M., Erdmann, V. A. & Betzel, C. (2004). Acta Cryst. D60, 1–7. CrossRef CAS IUCr Journals Google Scholar
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