 | Acta Crystallographica Section F Acta Crystallographica Section F STRUCTURAL BIOLOGY COMMUNICATIONS |
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![[Figure 5]](uf5017fig5mag.jpg)
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Figure 5
Structural variability within crystal structures of the free human fascin1 protein. Ribbon representations of molecule A (left panel) and molecule B (right panel) from various crystal structures of human fascin1. Structures shown include wild-type fascin1 from the present study (yellow for molecule A, green for molecule B), wild-type fascin1 from PDB entry 3llp (Chen et al., 2010  ; black), wild-type fascin1 from PDB entry 3p53 (Jansen et al., 2011; red) and the inactive S39D mutant from PDB entry 4gov (Yang et al., 2013; blue). To highlight conformational differences and domain flexibility, all structures were superposed based on β-trefoil domain 2. The comparisons reveal variations in domain orientations that underline the structural plasticity of fascin1 and its functional regulation. |
![[Figure 5]](uf5017fig5.jpg)
| STRUCTURAL BIOLOGY COMMUNICATIONS |
ISSN: 2053-230X
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