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Figure 1
The PvMIF monomer. (a) Cartoon representation of a PvMIF monomer colored in rainbow from blue at the N-terminus to red at the C-terminus. (b) Superposed monomers of PDB entry 9b0m (gray) with PDB entries 9mf3 (lemon green), 2wkf (magenta), 4p7m (tan), 3gac (wheat), 2wkb (cyan), 4dh4 (slate blue), 8ap3 (orange), 8ur2 (green), 8vj2 (smudge green) and 2xcz (yellow), the orthologues identified by ENDScript that were used to generate the sausage plot (Dobson et al., 2009View full citation; Pantouris et al., 2014View full citation; Shao et al., 2010View full citation; Sommerville et al., 2013View full citation; Spiller et al., 2023View full citation; Srivastava et al., 2024View full citation; Kimble et al., 2024View full citation; Wasiel et al., 2010View full citation). (c) PvMIF sausage plot generated by ENDScript. The ribbon (sausage) shows the relative conservation of secondary structure compared with the closest MIF structures. The ribbon thickness reflects the degree of secondary-structure similarity, with thinner ribbons indicating more conserved regions and thicker ribbons indicating lower conservation, as determined by r.m.s.d. alignment of the structures in (c). The ribbon is colored based on sequence conservation, with red indicating identical residues (a), (b) and (c) show the same view and orientation of PvMIF. The C-terminus and N-terminus are indicated by C and N, respectively.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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