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Figure 3
ESPript structure-based alignment with Clustal Omega sequence alignment of PvMIF (PDB entry 9b0m), human MIF1 (PDB entry 1mif), human MIF2 (PDB entry 1ddt) and PfMIF (PDB entry 2wkf). Human MIF residues implicated in CD74 binding are indicated with green boxes. The secondary-structure elements are as follows: α-helices are shown as large coils, 310-helices are shown as small coils labeled h, β-strands are shown as arrows labeled β and β-turns are labeled TT. The identical residues are shown in a white font on a red background, conserved residues in a red font and conserved regions in blue boxes. The sequence alignment was performed using ClustalW and was followed by ESPript structure alignment.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
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