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Figure 2
Positioning of the α1-helix near the active-site pocket of EcDSCD. (a) Monomer superposition of the five available EcDSCD structures showing the conserved topology but variable orientations of the α1-helix. (b) Surface representation of the EcDSCD trimer showing the active-site pocket near the α1-helix region. (c) Close-up comparison of the α1-helix positions in the present structure and PDB entry 6pbr near the active-site entrance. In the present structure, the α1-helix lies adjacent to Arg185 and the catalytic residues His376 and Asp380, positioning it above the entrance to the active-site pocket.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 82| Part 10| October 2026|
https://doi.org/10.1107/S2053230X2600909X