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Figure 3
Structural comparison of rBoNT/A with native BoNT/A at the active site. (a) Ribbon representation of the rBoNT/A LC structure. The four flexible active-site loops are highlighted in cyan (50/60 loop), magenta (170 loop), orange (250 loop) and red (370 loop). (b) Densities of the side chains of His228, Glu229, His232 and Glu267 involved in the network at the Zn2+ binding site. (c) Side view of the superimposition of LC of rBoNT/A (blue) and native BoNT/A (PDB entry 3bta, wheat) and (d) enlarged view.

Journal logoSTRUCTURAL BIOLOGY
COMMUNICATIONS
ISSN: 2053-230X
Volume 82| Part 11| November 2026| Pages 391-401
https://doi.org/10.1107/S2053230X26009830