Crystal structure of the bifunctional enzyme phosphoribosyl isomerase A from Mycobacterium tuberculosis with bound light-controllable inhibitor

Rajendran, C.; Sterner, R.

doi:10.1107/S2053230X26009684

Figure 4
Cartoon representation of mtPriA (pale green) with bound inhibitor DTE LC6-1 (red). Loop 5 with residues EHRL forming an additional short β-strand is highlighted in pink. In the insets, the residues in wheat show the N-terminal (Gly83, Gly104, Thr105, Ala106) and C-terminal (Gly176, Gly202, Gly226, Lys227) residues involved in binding of the terminal phosphates of DTE LC6-1 (see Table 2

and Supplementary Fig. S2).

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Volume 82| Part 11| November 2026| Pages 385-390

https://doi.org/10.1107/S2053230X26009684

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