most read articles

These are the most read articles in the last six months.

Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms. M. Sharma, A. Cuetos, A. Willliams, D. González-Martínez & G. Grogan (2023). Acta Cryst. F79, 224-230.

High-resolution crystal structure of the Mu8.1 conotoxin from Conus mucronatus. E. Müller, C. M. Hackney, L. Ellgaard & J. P. Morth (2023). Acta Cryst. F79, 240-246.

Joint X-ray/neutron structure of Lentinus similis AA9_A at room temperature. T. Tandrup, L. Lo Leggio & F. Meilleur (2023). Acta Cryst. F79, 1-7.

Structures of chloramphenicol acetyltransferase III and Escherichia coli β-ketoacylsynthase III co-crystallized with partially hydrolysed acetyl-oxa(dethia)CoA. A. B. Benjamin, L. M. Stunkard, J. Ling, J. N. Nice & J. R. Lohman (2023). Acta Cryst. F79, 61-69.

Biochemical and X-ray analyses of the players involved in the faRel2/aTfaRel2 toxin–antitoxin operon. L. Dominguez-Molina, A. Talavera, A. Cepauskas, T. Kurata, D. Echemendia-Blanco, V. Hauryliuk & A. Garcia-Pino (2023). Acta Cryst. F79, 247-256.

Making your raw data available to the macromolecular crystallography community. L. M. J. Kroon-Batenburg (2023). Acta Cryst. F79, 267-273.

Room-temperature serial synchrotron crystallography of the human phosphatase PTP1B. S. Sharma, A. Ebrahim & D. A. Keedy (2023). Acta Cryst. F79, 23-30.

Structural and biophysical characterization of the Borna disease virus 1 phosphoprotein. J. D. Whitehead, J. M. Grimes & J. R. Keown (2023). Acta Cryst. F79, 51-60.

Purification and structure of luminal domain C of human Niemann–Pick C1 protein. L. Odongo, K. K. Zadrozny, W. E. Diehl, J. Luban, J. M. White, B. K. Ganser-Pornillos, L. K. Tamm & O. Pornillos (2023). Acta Cryst. F79, 45-50.

Crystal structure of adenylosuccinate lyase from the thermophilic bacterium Thermus thermophilus HB8. N. Nemoto, G. Kawai & G. Sampei (2023). Acta Cryst. F79, 278-284.

A triumvirate of Section Editors moving Structural Biology Communications ahead. M. van Raaij (2023). Acta Cryst. F79, 276-277.

Crystal structure of Prp16 in complex with ADP. T. B. Garbers, M. Enders, P. Neumann & R. Ficner (2023). Acta Cryst. F79, 200-207.

Tetracycline-modifying enzyme SmTetX from Stenotrophomonas maltophilia. M. Malý, P. Kolenko, J. Stránský, L. Švecová, J. Dušková, T. Koval', T. Skálová, M. Trundová, K. Adámková, J. Černý, P. Božíková & J. Dohnálek (2023). Acta Cryst. F79, 180-192.

Crystal structures of glutamyl-tRNA synthetase from Elizabethkingia anopheles and E. meningosepticum. L. Brooks, S. Subramanian, D. M. Dranow, S. J. Mayclin, P. J. Myler & O. A. Asojo (2022). Acta Cryst. F78, 306-312.

Crystal structure of a GCN5-related N-acetyltransferase from Lactobacillus curiae. J. R. Fleming, F. Hauth, J. S. Hartig & O. Mayans (2023). Acta Cryst. F79, 217-223.

Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2. A. Stewart, P. Dershwitz, C. Stewart Jr, M. R. Sawaya, T. O. Yeates, J. D. Semrau, H. Zischka, A. A. DiSpirito & T. A. Bobik (2023). Acta Cryst. F79, 111-118.

AlphaFold and the future of structural biology. R. J. Read, E. N. Baker, C. S. Bond, E. F. Garman & M. J. van Raaij (2023). Acta Cryst. F79, 166-168.

Drastic alterations in the loop structure around colchicine upon complex formation with an engineered lipocalin indicate a conformational selection mechanism. E. Jerschke, A. Eichinger & A. Skerra (2023). Acta Cryst. F79, 231-239.

The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis. N. Schormann, M. Patel, L. Thannickal, S. Purushotham, R. Wu, J. L. Mieher, H. Wu & C. Deivanayagam (2023). Acta Cryst. F79, 119-127.

Monomeric crystal structure of the vaccine carrier protein CRM₁₉₇ and implications for vaccine development. D. T. Gallagher, N. Oganesyan & A. Lees (2023). Acta Cryst. F79, 82-86.

The structure of a tautomerase superfamily member linked to the type VI secretion system of Acinetobacter baumannii. G. Pankov, G. Mol Avelar, G. Buchanan, S. J. Coulthurst & W. N. Hunter (2023). Acta Cryst. F79, 8-16.

Using structural genomics depositions in undergraduate teaching of protein crystallography: everybody wins. J. Agirre (2023). Acta Cryst. F79, 274-275.

Crystal structure of an inorganic pyrophosphatase from Chlamydia trachomatis D/UW-3/Cx. J. Maddy, B. L. Staker, S. Subramanian, J. Abendroth, T. E. Edwards, P. J. Myler, K. Hybiske & O. A. Asojo (2022). Acta Cryst. F78, 135-142.

Crystal structure of the Rho-associated coiled-coil kinase 2 inhibitor belumosudil bound to CK2α. P. Brear & M. Hyvönen (2022). Acta Cryst. F78, 348-353.

Erwinia tasmaniensis levansucrase shows enantiomer selection for (S)-1,2,4-butanetriol. I. Polsinelli, M. Salomone-Stagni & S. Benini (2022). Acta Cryst. F78, 289-296.

Structure of the Monkeypox virus profilin-like protein A42R reveals potential functional differences from cellular profilins. G. Minasov, N. L. Inniss, L. Shuvalova, W. F. Anderson & K. J. F. Satchell (2022). Acta Cryst. F78, 371-377.

Crystal structure of the ternary complex of Leishmania major pteridine reductase 1 with the cofactor NADP⁺/NADPH and the substrate folic acid. L. Dello Iacono, F. Di Pisa & S. Mangani (2022). Acta Cryst. F78, 170-176.

Variations on a theme: crystal forms of the amino-acid transporter MhsT. C. Neumann, D. Focht, S. Trampari, J. A. Lyons & P. Nissen (2022). Acta Cryst. F78, 297-305.

6-Phosphogluconate dehydrogenase and its crystal structures. S. Hanau & J. R. Helliwell (2022). Acta Cryst. F78, 96-112.

Crystals of SctV from different species reveal variable symmetry for the cytosolic domain of the type III secretion system export gate. D. Gilzer, E. Baum, N. Lieske, J. L. Kowal & H. H. Niemann (2022). Acta Cryst. F78, 386-394.

Biochemical and crystallization analysis of the CENP-SX–DNA complex. S. Ito & T. Nishino (2022). Acta Cryst. F78, 193-199.

Expression, purification and crystallization of a novel metagenome-derived salicylaldehyde dehydrogenase from Alpine soil. S. U. Dandare, M. Håkansson, L. A. Svensson, D. J. Timson & C. C. R. Allen (2022). Acta Cryst. F78, 161-169.

The structure of Synechococcus elongatus enolase reveals key aspects of phosphoenolpyruvate binding. J. M. González, R. Martí-Arbona, J. C.-H. Chen & C. J. Unkefer (2022). Acta Cryst. F78, 177-184.

Delineating the activity of the potent nicotinic acetylcholine receptor agonists (+)-anatoxin-a and (−)-hosieine-A. H. P. Parker, A. Dawson, M. J. Jones, R. Yan, J. Ouyang, R. Hong & W. N. Hunter (2022). Acta Cryst. F78, 313-323.

In situ crystal data-collection and ligand-screening system at SPring-8. H. Okumura, N. Sakai, H. Murakami, N. Mizuno, Y. Nakamura, G. Ueno, T. Masunaga, T. Kawamura, S. Baba, K. Hasegawa, M. Yamamoto & T. Kumasaka (2022). Acta Cryst. F78, 241-251.

Crystal structure of the kringle domain of human receptor tyrosine kinase-like orphan receptor 1 (hROR1). S. R. Guarino, A. Di Bello, M. Palamini, M. C. Capillo & F. Forneris (2022). Acta Cryst. F78, 185-192.

Conformational flexibility in the zinc solute-binding protein ZnuA. E. L. Yekwa, F. A. Serrano & E. Yukl (2022). Acta Cryst. F78, 128-134.

Relating protein crystal structure to ligand-binding thermodynamics. J. R. Helliwell (2022). Acta Cryst. F78, 403-407.

Introduction to the virtual thematic issue on room-temperature biological crystallography. R. A. Steiner (2023). Acta Cryst. F79, 79-81.

Serial crystallography with multi-stage merging of thousands of images. A. S. Soares, Y. Yamada, J. Jakoncic, S. McSweeney, R. M. Sweet, J. Skinner, J. Foadi, M. R. Fuchs, D. K. Schneider, W. Shi, B. Andi, L. C. Andrews & H. J. Bernstein (2022). Acta Cryst. F78, 281-288.

Crystal structure of betaine aldehyde dehydrogenase from Burkholderia pseudomallei. D. K. Beard, S. Subramanian, J. Abendroth, D. M. Dranow, T. E. Edwards, P. J. Myler & O. A. Asojo (2022). Acta Cryst. F78, 45-51.

Structure of angiogenin dimer bound to double-stranded RNA. K. Sievers & R. Ficner (2022). Acta Cryst. F78, 330-337.

Crystal structure of a hypothetical protein from Giardia lamblia. Corrigendum. D. K. Beard, S. Bristol, K. Cosby, A. Davis, C. Manning, L. Perry, L. Snapp, A. Toy, K. Wheeler, J. Young, B. Staker, T. L. Arakaki, J. Abendroth, S. Subramanian, T. E. Edwards, P. J. Myler & O. A. Asojo (2022). Acta Cryst. F78, 143.

Crystal structure of a short-chain dehydrogenase/reductase from Burkholderia phymatum in complex with NAD. J. Alenazi, S. Mayclin, S. Subramanian, P. J. Myler & O. A. Asojo (2022). Acta Cryst. F78, 52-58.

The crystal structure of DynF from the dynemicin-biosynthesis pathway of Micromonospora chersina. A. J. Kosgei, M. D. Miller, M. Bhardwaj, W. Xu, J. S. Thorson, S. G. Van Lanen & G. N. Phillips Jr (2022). Acta Cryst. F78, 1-7.

The structure of His-tagged Geobacillus stearothermophilus purine nucleoside phosphorylase reveals a `spanner in the works'. F. M. Given, F. Moran, A. S. Johns, J. A. Titterington, T. M. Allison, D. L. Crittenden & J. M. Johnston (2022). Acta Cryst. F78, 416-422.

Ibuprofen: a weak inhibitor of carbonic anhydrase II. J. Combs, J. Andring & R. McKenna (2022). Acta Cryst. F78, 395-402.

Crystal structure of a hypothetical protein from Giardia lamblia. D. K. Beard, S. Bristol, K. Cosby, A. Davis, C. Manning, L. Perry, L. Snapp, A. Toy, K. Wheeler, J. Young, B. Staker, T. L. Arakaki, J. Abendroth, S. Subrahamanian, T. E. Edwards, P. J. Myler & O. A. Asojo (2022). Acta Cryst. F78, 59-65.

A crystal-processing machine using a deep-ultraviolet laser: application to long-wavelength native SAD experiments. Y. Kawano, M. Hikita, N. Matsugaki, M. Yamamoto & T. Senda (2022). Acta Cryst. F78, 88-95.

Crystal structures of the ligand-binding domain of human peroxisome proliferator-activated receptor δ in complexes with phenylpropanoic acid derivatives and a pyridine carboxylic acid derivative. T. Oyama, K. Takiguchi & H. Miyachi (2022). Acta Cryst. F78, 81-87.

Crystal structure of an extracellular superoxide dismutase from Onchocerca volvulus and implications for parasite-specific drug development. A. Moustafa, M. Perbandt, E. Liebau, C. Betzel & S. Falke (2022). Acta Cryst. F78, 232-240.

Crystallization and preliminary X-ray analysis of the C-type lectin domain of the spicule matrix protein SM50 from Strongylocentrotus purpuratus. Corrigendum. R. Ebenhoch, P. Juneja, A. Rao, H. Cölfen, K. Diederichs & W. Welte (2022). Acta Cryst. F78, 347.

Cryotrapping peroxide in the active site of human mitochondrial manganese superoxide dismutase crystals for neutron diffraction. J. Azadmanesh, W. E. Lutz, L. Coates, K. L. Weiss & G. E. O. Borgstahl (2022). Acta Cryst. F78, 8-16.

Crystal structures of FolM alternative dihydrofolate reductase 1 from Brucella suis and Brucella canis. I. Porter, T. Neal, Z. Walker, D. Hayes, K. Fowler, N. Billups, A. Rhoades, C. Smith, K. Smith, B. L. Staker, D. M. Dranow, S. J. Mayclin, S. Subramanian, T. E. Edwards, P. J. Myler & O. A. Asojo (2022). Acta Cryst. F78, 31-38.

Crystallization and low-resolution structure solution of the SALM3–PTPσ synaptic adhesion complex. S. Karki & T. Kajander (2022). Acta Cryst. F78, 39-44.

X-ray structure of a human cardiac muscle troponin C/troponin I chimera in two crystal forms. C. Yan & J. S. Sack (2022). Acta Cryst. F78, 17-24.

Crystal structure of a putative short-chain dehydrogenase/reductase from Paraburkholderia xenovorans. J. Davidson, K. Nicholas, J. Young, D. G. Conrady, S. Mayclin, S. Subramanian, B. L. Staker, P. J. Myler & O. A. Asojo (2022). Acta Cryst. F78, 25-30.

Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1. J. Moorefield, Y. Konuk, J. O. Norman, J. Abendroth, T. E. Edwards, D. D. Lorimer, S. J. Mayclin, B. L. Staker, J. K. Craig, K. F. Barett, L. K. Barrett, W. C. Van Voorhis, P. J. Myler & K. J. McLaughlin (2023). Acta Cryst. F79, 257-266.

Structural basis for the development of potential inhibitors targeting FadD23 from Mycobacterium tuberculosis. M. Yan, M. Ma, R. Chen, Y. Cao, W. Zhang & X. Liu (2023). Acta Cryst. F79, 208-216.

Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1. K.-S. Sim & T. Inoue (2023). Acta Cryst. F79, 169-179.

Crystal structure of CmnB involved in the biosynthesis of the nonproteinogenic amino acid L-2,3-diaminopropionic acid. S.-I. Toh, C.-L. Lo & C.-Y. Chang (2023). Acta Cryst. F79, 193-199.

Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli. K. Matsumoto, Y. Fukuda & T. Inoue (2023). Acta Cryst. F79, 285-293.

Crystal structure of a three-tetrad, parallel, K⁺-stabilized human telomeric G-quadruplex at 1.35 Å resolution. E. V. Chen, J. M. Nicoludis, B. M. Powell, K. S. Li & L. A. Yatsunyk (2023). Acta Cryst. F79, 144-150.

Crystal structure of thermostable acetaldehyde dehydrogenase from the hyperthermophilic archaeon Sulfolobus tokodaii. S. Mine, M. Nakabayashi & K. Ishikawa (2023). Acta Cryst. F79, 159-165.

A partially open conformation of an androgen receptor ligand-binding domain with drug-resistance mutations. S. K. Doamekpor, P. Peng, R. Xu, L. Ma, Y. Tong & L. Tong (2023). Acta Cryst. F79, 95-104.

Bacterial structural genomics target enabled by a recently discovered potent fungal acetyl-CoA synthetase inhibitor. N. D. DeBouver, M. J. Bolejack, T. E. Esan, D. J. Krysan, T. J. Hagen & J. Abendroth (2023). Acta Cryst. F79, 137-143.

Crystal structure of the engineered endolysin mtEC340M. J.-M. Wang, S.-H. Seok, W.-S. Yoon, J.-H. Kim & M.-D. Seo (2023). Acta Cryst. F79, 105-110.

Structure of pyridoxal 5′-phosphate-bound D-threonine aldolase from Chlamydomonas reinhardtii. Y. Hirato, M. Goto, T. Mizobuchi, H. Muramatsu, M. Tanigawa & K. Nishimura (2023). Acta Cryst. F79, 31-37.

Structural and enzymatic characterization of the sialidase SiaPG from Porphyromonas gingivalis. W.-B. Dong, Y.-L. Jiang, Z.-L. Zhu, J. Zhu, Y. Li, R. Xia & K. Zhou (2023). Acta Cryst. F79, 87-94.

Expression, purification and crystallization of N-acetyl-(R)-β-phenylalanine acylases derived from Burkholderia sp. AJ110349 and Variovorax sp. AJ110348 and structure determination of the Burkholderia enzyme. Y. Kato, H. Kawasaki, T. Nakamatsu, N. Matsuda & R. Natsume (2023). Acta Cryst. F79, 70-78.

Structural and functional analysis of the SET3 histone deacetylase complex. A. A. Reyes, S. Fishbain & Y. He (2022). Acta Cryst. F78, 113-118.

Crystal structure of MAB_4123, a putative flavin-dependent monooxygenase from Mycobacterium abscessus. K. L. Ung, C. Poussineau, J. Couston, H. M. A. B. Alsarraf & M. Blaise (2023). Acta Cryst. F79, 128-136.

The crystal structure of the human smacovirus 1 Rep domain. L. K. Limón, K. Shi, A. Dao, J. Rugloski, K. J. Tompkins, H. Aihara, W. R. Gordon & R. L. Evans III (2023). Acta Cryst. F79, https://doi.org/10.1107/S2053230X23009536.

Crystal structure of the C-terminal domain of the plant-specific microtubule-associated protein Spiral2. M. Ohno, Y. Higuchi & I. Hayashi (2023). Acta Cryst. F79, 17-22.

Crystal structure determination of the halogenase CtcP from Streptomyces aureofaciens. L. Yin (2022). Acta Cryst. F78, 270-275.

Crystal structure of Sphingobacterium multivorum serine palmitoyltransferase complexed with tris(hydroxymethyl)aminomethane. H. Ikushiro, A. Takahashi, T. Murakami, A. Katayama, T. Sawai, H. Goto, I. Miyahara, N. Kamiya & T. Yano (2022). Acta Cryst. F78, 408-415.

Structural study of Legionella pneumophila effector DotY (Lpg0294), a component of the Dot/Icm type IV secretion system. I. Y. W. Chung & M. Cygler (2022). Acta Cryst. F78, 276-280.

Crystal structure of a putative 3-hydroxypimelyl-CoA dehydrogenase, Hcd1, from Syntrophus aciditrophicus strain SB at 1.78 Å resolution. D. M. Dinh, L. M. Thomas & E. A. Karr (2023). Acta Cryst. F79, 151-158.

Structural and spectroscopic characterization of CO inhibition of [NiFe]-hydrogenase from Citrobacter sp. S-77. T. Imanishi, K. Nishikawa, M. Taketa, K. Higuchi, H. Tai, S. Hirota, H. Hojo, T. Kawakami, K. Hataguchi, K. Matsumoto, H. Ogata & Y. Higuchi (2022). Acta Cryst. F78, 66-74.

An unusual disulfide-linked dimerization in the fluorescent protein rsCherryRev1.4. T. Y. H. Bui, P. Dedecker & L. Van Meervelt (2023). Acta Cryst. F79, 38-44.

Structure of the hypothetical protein TTHA1873 from Thermus thermophilus. I. Yuvaraj, S. K. Chaudhary, J. Jeyakanthan & K. Sekar (2022). Acta Cryst. F78, 338-346.

Crystal structure of the PX domain of Vps17p from Saccharomyces cerevisiae. T. Obita, K. Inaka, D. Kohda & N. Maita (2022). Acta Cryst. F78, 210-216.

Purification, crystallization and crystallographic analysis of the PorX response regulator associated with the type IX secretion system. A. Saran, N. Weerasinghe, C. J. Thibodeaux & N. Zeytuni (2022). Acta Cryst. F78, 354-362.

Crystal structure of the capsular polysaccharide-synthesis enzyme CapG from Staphylococcus aureus. N. Tien, C.-Y. Ho, S.-J. Lai, Y.-C. Lin, C.-S. Yang, Y.-C. Wang, W.-C. Huang, Y. Chen & J.-J. Chang (2022). Acta Cryst. F78, 378-385.

Structural characterization of the urease accessory protein UreF from Klebsiella pneumoniae. S. Liu, W. Wu, Q. Zhao, H. Liang, S. Che, H. Zhang, R. Liu, Q. Zhang & M. Bartlam (2022). Acta Cryst. F78, 75-80.

The structure of succinyl-CoA synthetase bound to the succinyl-phosphate intermediate clarifies the catalytic mechanism of ATP-citrate lyase. J. Huang & M. E. Fraser (2022). Acta Cryst. F78, 363-370.

Structure and activity of a thermally stable mutant of Acanthamoeba actophorin. S. Quirk & R. L. Lieberman (2022). Acta Cryst. F78, 150-160.

Effects of the T337M and G391V disease-related variants on human phosphoglucomutase 1: structural disruptions large and small. K. M. Stiers, L. F. Owuocha & L. J. Beamer (2022). Acta Cryst. F78, 200-209.

Identification, structure determination and analysis of Mycobacterium smegmatis acyl-carrier protein synthase (AcpS) crystallized serendipitously. I. Bhatia, S. Yadav & B. K. Biswal (2022). Acta Cryst. F78, 252-264.

Structural investigation of a pyrano-1,3-oxazine derivative and the phenanthridinone core moiety against BRD2 bromodomains. A. H. Arole, P. Deshmukh, A. Sridhar & B. Padmanabhan (2022). Acta Cryst. F78, 119-127.

Crystallization and crystallographic studies of a novel chickpea 11S globulin. L. Sun, A. Zhou & F. Zhang (2022). Acta Cryst. F78, 324-329.

Preliminary XFEL data from spontaneously grown endo-1,4-β-xylanase crystals from Hypocrea virens. K. H. Nam, S. Park & J. Park (2022). Acta Cryst. F78, 226-231.

Crystal structure of thermally stable homodimeric cytochrome c′-β from Thermus thermophilus. T. Yoshimi, S. Fujii, H. Oki, T. Igawa, H. R. Adams, K. Ueda, K. Kawahara, T. Ohkubo, M. A. Hough & Y. Sambongi (2022). Acta Cryst. F78, 217-225.

Crystal structure of the catalytic domain of human RPTPH. M. Kim & S. E. Ryu (2022). Acta Cryst. F78, 265-269.

Structure of BrxA from Staphylococcus aureus, a bacilliredoxin involved in redox homeostasis in Firmicutes. C. S. McHugh & P. D. Cook (2022). Acta Cryst. F78, 144-149.

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