most read articles
These are the most read articles in the last six months.
Multi-species cryoEM calibration and workflow verification standard. (2024). Acta Cryst. F80, 320-327.
Co-crystal structure of Helicobacter pylori biotin protein ligase with biotinyl-5-ATP. (2025). Acta Cryst. F81, 11-18.
CryoCrane: an open-source GUI for analyzing cryo-EM screening data sets. (2025). Acta Cryst. F81, 62-65.
Human transforming growth factor β type I receptor in complex with kinase inhibitor SB505124. (2024). Acta Cryst. F80, 314-319.
Crystal structure of N-terminally hexahistidine-tagged Onchocerca volvulus macrophage migration inhibitory factor-1. (2024). Acta Cryst. F80, 328-334.
The first report of structural analysis of a nucleic acid using crystals grown in space. (2025). Acta Cryst. F81, 95-100.
Glucose-6-phosphate dehydrogenase and its 3D structures from crystallography and electron cryo-microscopy. (2024). Acta Cryst. F80, 236-251.
X-ray crystal structure of proliferating cell nuclear antigen 1 from Aeropyrum pernix. (2024). Acta Cryst. F80, 294-301.
Structures of Trichomonas vaginalis macrophage migratory inhibitory factor. (2024). Acta Cryst. F80, 341-347.
Crystal structure of glutamyl-tRNA synthetase from Helicobacter pylori. (2024). Acta Cryst. F80, 335-340.
LOPAC library screening identifies suramin as a TRIM21 binder with a unique binding mode revealed by crystal structure. (2025). Acta Cryst. F81, 101-107.
Preparing research samples for safe arrival at centers and facilities: recipes for successful experiments. (2024). Acta Cryst. F80, 165-172.
Ternary structure of Plasmodium vivax N-myristoyltransferase with myristoyl-CoA and inhibitor IMP-0001173. (2024). Acta Cryst. F80, 269-277.
Crystallization and crystallographic studies of human serine protease inhibitor (serpin) B9. (2024). Acta Cryst. F80, 286-293.
Crystal structure of a short-chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP+ and benzoic acid. (2024). Acta Cryst. F80, 348-355.
Serendipitous high-resolution structure of Escherichia coli carbonic anhydrase 2. (2025). Acta Cryst. F81, 47-52.
The structure of His15 acetamide-modified hen egg-white lysozyme: a nice surprise from an old friend. (2025). Acta Cryst. F81, 41-46.
Improving the diffraction quality of heat-shock protein 47 crystals. (2024). Acta Cryst. F80, 302-313.
Revisiting sodium phosphotungstate and ammonium molybdate as nonradioactive negative-staining agents for single-particle analysis. (2024). Acta Cryst. F80, 356-362.
Tetracycline-modifying enzyme SmTetX from Stenotrophomonas maltophilia. (2023). Acta Cryst. F79, 180-192.
First crystal structure of the DUF2436 domain of virulence proteins from Porphyromonas gingivalis. (2024). Acta Cryst. F80, 252-262.
Cryo-EM structures of apo and atorvastatin-bound human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. (2025). Acta Cryst. F81, 118-122.
The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. (2025). Acta Cryst. F81, 124-129.
The first report of structural analysis of a nucleic acid using crystals grown in space. Corrigendum. (2025). Acta Cryst. F81, 177-178.
Crystal structure of guanosine 5′-monophosphate synthetase from the thermophilic bacterium Thermus thermophilus HB8. (2024). Acta Cryst. F80, 278-285.
Crystallographic fragment screen of the c-di-AMP-synthesizing enzyme CdaA from Bacillus subtilis. (2024). Acta Cryst. F80, 200-209.
Crystallization and preliminary X-ray crystallographic studies of AfeH from Acimetobacter sp. DL-2. (2025). Acta Cryst. F81, 30-34.
The catalytic domains of Streptococcus mutans glucosyltransferases: a structural analysis. (2023). Acta Cryst. F79, 119-127.
The crystal structures of apo and tryptophan-bound tryptophanyl-tRNA synthetase from Neisseria gonorrhoeae. (2025). Acta Cryst. F81, 130-137.
X-ray crystal structure of a designed rigidified imaging scaffold in the ligand-free conformation. (2024). Acta Cryst. F80, 107-115.
Structures of Mycobacterium tuberculosis isoprenyl diphosphate synthase Rv2173 in substrate-bound forms. (2025). Acta Cryst. F81, https://doi.org/10.1107/S2053230X25002298.
Crystal structure of the S-adenosylmethionine-dependent mycolic acid synthase UmaA from Mycobacterium tuberculosis. (2025). Acta Cryst. F81, 146-154.
The impact of exchanging the light and heavy chains on the structures of bovine ultralong antibodies. (2024). Acta Cryst. F80, 154-163.
Crystal structure of dihydroorotate dehydrogenase from Helicobacter pylori with bound flavin mononucleotide. (2025). Acta Cryst. F81, 108-117.
Protein expression, purification, crystallization and crystallographic studies of BPSL0741 from Burkholderia pseudomallei. (2024). Acta Cryst. F80, 263-268.
Online carbohydrate 3D structure validation with the Privateer web app. (2024). Acta Cryst. F80, 30-35.
Room-temperature serial synchrotron crystallography structure of Spinacia oleracea RuBisCO. (2024). Acta Cryst. F80, 117-124.
Crystallographic analysis of the Escherichia coli tRNA seleno-modification enzyme in complex with tRNA. (2025). Acta Cryst. F81, 35-40.
Structure of the outer membrane porin OmpW from the pervasive pathogen Klebsiella pneumoniae. (2024). Acta Cryst. F80, 22-27.
Crystal structure of the RNA-recognition motif of Drosophila melanogaster tRNA (uracil-5-)-methyltransferase homolog A. (2024). Acta Cryst. F80, 36-42.
The structure of a pectin-active family 1 polysaccharide lyase from the marine bacterium Pseudoalteromonas fuliginea. (2024). Acta Cryst. F80, 142-147.
Structural and biochemical characterization of the M405S variant of Desulfovibrio vulgaris formate dehydrogenase. (2024). Acta Cryst. F80, 98-106.
Crystal structure of MbnF: an NADPH-dependent flavin monooxygenase from Methylocystis strain SB2. (2023). Acta Cryst. F79, 111-118.
Expression, purification and crystallization of the photosensory module of phytochrome B (phyB) from Sorghum bicolor. (2024). Acta Cryst. F80, 59-66.
Analysis of Burkholderia pseudomallei IspF in complex with sulfapyridine, sulfamonomethoxine, ethoxzolamide and acetazolamide. (2025). Acta Cryst. F81, 138-145.
Crystal structure of adenylosuccinate lyase from the thermophilic bacterium Thermus thermophilus HB8. (2023). Acta Cryst. F79, 278-284.
Structural characterization of dUTPase from Legionella pneumophila. (2025). Acta Cryst. F81, 155-162.
High-resolution crystal structure of the Mu8.1 conotoxin from Conus mucronatus. (2023). Acta Cryst. F79, 240-246.
Making your raw data available to the macromolecular crystallography community. (2023). Acta Cryst. F79, 267-273.
Crystal structure of a GCN5-related N-acetyltransferase from Lactobacillus curiae. (2023). Acta Cryst. F79, 217-223.
Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites. (2024). Acta Cryst. F80, 210-219.
Structures of Legionella pneumophila serogroup 1 peptide deformylase bound to nickel(II) and actinonin. (2025). Acta Cryst. F81, 163-170.
Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms. (2023). Acta Cryst. F79, 224-230.
Using structural genomics depositions in undergraduate teaching of protein crystallography: everybody wins. (2023). Acta Cryst. F79, 274-275.
Crystal structures of the 3C proteases from Coxsackievirus B3 and B4. (2024). Acta Cryst. F80, 183-190.
Crystal structures of NAD(P)H nitroreductases from Klebsiella pneumoniae. (2024). Acta Cryst. F80, 173-182.
Cryo-EM structure and functional analysis of the chromatin remodeler RSF. (2024). Acta Cryst. F80, 125-134.
Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1. (2023). Acta Cryst. F79, 257-266.
Biochemical and X-ray analyses of the players involved in the faRel2/aTfaRel2 toxin–antitoxin operon. (2023). Acta Cryst. F79, 247-256.
Structure of a superoxide dismutase from a tardigrade: Ramazzottius varieornatus strain YOKOZUNA-1. (2023). Acta Cryst. F79, 169-179.
The importance of international collaborations in science and structural biology. (2024). Acta Cryst. F80, 116.
Crystallization and biochemical studies of the NYN domain of human KHNYN. (2024). Acta Cryst. F80, 67-72.
Crystal structure of the GDP-bound human M-RAS protein in two crystal forms. (2024). Acta Cryst. F80, 220-227.
Structural and functional characterization of FabG4 from Mycolicibacterium smegmatis. (2024). Acta Cryst. F80, 82-91.
Biochemical and structural characterization of a class A β-lactamase from Nocardia cyriacigeorgica. (2024). Acta Cryst. F80, 13-21.
Crystal structure of the Rib domain of the cell-wall-anchored surface protein from Limosilactobacillus reuteri. (2024). Acta Cryst. F80, 228-233.
Structural basis for the development of potential inhibitors targeting FadD23 from Mycobacterium tuberculosis. (2023). Acta Cryst. F79, 208-216.
Structural analysis of the FERM domain of human protein tyrosine phosphatase non-receptor type 21. (2024). Acta Cryst. F80, 148-153.
Crystal structure of the long Rib domain of the LPXTG-anchored surface protein from Limosilactobacillus reuteri. (2024). Acta Cryst. F80, 92-97.
Crystal structure and biophysical characterization of IspD from Burkholderia thailandensis and Mycobacterium paratuberculosis. (2024). Acta Cryst. F80, 43-51.
Crystal structures of QseE and QseG: elements of a three-component system from Escherichia coli. (2023). Acta Cryst. F79, 285-293.
Molecular interactions between piperine and peroxisome proliferator-activated receptor gamma ligand-binding domain revealed using co-crystallization studies. (2025). Acta Cryst. F81, https://doi.org/10.1107/S2053230X25002377.
Direct relationship between dimeric form and activity in the acidic copper–zinc superoxide dismutase from lemon. (2023). Acta Cryst. F79, 301-307.
Bacterial structural genomics target enabled by a recently discovered potent fungal acetyl-CoA synthetase inhibitor. (2023). Acta Cryst. F79, 137-143.
Crystal structure of CmnB involved in the biosynthesis of the nonproteinogenic amino acid L-2,3-diaminopropionic acid. (2023). Acta Cryst. F79, 193-199.