most read articles
These are the most read articles in the last six months.
Crystal structure of Methanococcus jannaschii dihydroorotase with substrate bound. (2026). Acta Cryst. F82, 23-31.
Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms. Corrigendum. (2026). Acta Cryst. F82, 41.
Potential 14-3-3 binding sites in sirtuins reveal extended phosphosite-recognition modes. (2026). Acta Cryst. F82, 32-40.
CryoSift: an accessible and automated CNN-driven tool for cryo-EM 2D class selection. (2025). Acta Cryst. F81, 517-526.
Crystal structure of a short-chain dehydrogenase from Brucella ovis with apo and coenzyme NAD+-bound protomer chains. (2025). Acta Cryst. F81, 487-494.
Triosephosphate isomerase from Fasciola hepatica: high-resolution crystal structure as a drug target. (2025). Acta Cryst. F81, 381-387.
The first report of structural analysis of a nucleic acid using crystals grown in space. (2025). Acta Cryst. F81, 95-100.
Structural insights into full-length human fascin1: a target for cancer treatment. (2025). Acta Cryst. F81, 319-331.
Crystallization and 1.6 Å resolution crystal structure of an acylated GLP-1/GIP analogue peptide. (2026). Acta Cryst. F82, 114-124.
Preparing research samples for safe arrival at centers and facilities: recipes for successful experiments. (2024). Acta Cryst. F80, 165-172.
LOPAC library screening identifies suramin as a TRIM21 binder with a unique binding mode revealed by crystal structure. (2025). Acta Cryst. F81, 101-107.
The impact of exchanging the light and heavy chains on the structures of bovine ultralong antibodies. (2024). Acta Cryst. F80, 154-163.
Glucose-6-phosphate dehydrogenase and its 3D structures from crystallography and electron cryo-microscopy. (2024). Acta Cryst. F80, 236-251.
Crystal structure of ATP-dependent DNA ligase from Rhizobium phage vB_RleM_P10VF. (2025). Acta Cryst. F81, 249-254.
First crystal structure of the DUF2436 domain of virulence proteins from Porphyromonas gingivalis. (2024). Acta Cryst. F80, 252-262.
Crystal structure of a short-chain dehydrogenase from Burkholderia cenocepacia J2315 in complex with NADP+ and benzoic acid. (2024). Acta Cryst. F80, 348-355.
Off-target binding of the histone deacetylase inhibitor vorinostat to carbonic anhydrase II and IX. (2025). Acta Cryst. F81, 388-397.
Nucleotide-bound crystal structures of the SARS-CoV-2 helicase NSP13. (2025). Acta Cryst. F81, 338-347.
Co-crystal structure of Helicobacter pylori biotin protein ligase with biotinyl-5-ATP. (2025). Acta Cryst. F81, 11-18.
High-resolution X-ray structure of Gln143Asn manganese superoxide dismutase captures multiple hydrogen peroxide-binding sites. (2025). Acta Cryst. F81, 467-477.
Revisiting sodium phosphotungstate and ammonium molybdate as nonradioactive negative-staining agents for single-particle analysis. (2024). Acta Cryst. F80, 356-362.
Serendipitous high-resolution structure of Escherichia coli carbonic anhydrase 2. (2025). Acta Cryst. F81, 47-52.
Ternary structure of Plasmodium vivax N-myristoyltransferase with myristoyl-CoA and inhibitor IMP-0001173. (2024). Acta Cryst. F80, 269-277.
Crystal structure of the sucrose phosphorylase from Alteromonas mediterranea shows a loop transition in the active site. (2025). Acta Cryst. F81, 306-310.
Human transforming growth factor β type I receptor in complex with kinase inhibitor SB505124. (2024). Acta Cryst. F80, 314-319.
Crystal structures of Escherichia coli glucokinase and insights into phosphate binding. (2025). Acta Cryst. F81, 332-337.
Crystal structure of a tRNA acceptor-stem mimic at 1.94 Å resolution. (2026). Acta Cryst. F82, 57-65.
Multi-species cryoEM calibration and workflow verification standard. (2024). Acta Cryst. F80, 320-327.
The structure of a family 168 glycoside hydrolase from the marine bacterium Muricauda eckloniae. (2025). Acta Cryst. F81, 281-286.
Structures of Listeria monocytogenes MenD in ThDP-bound and in-crystallo captured intermediate I-bound forms. (2025). Acta Cryst. F81, 348-357.
Crystal structure of the folded domains of Xrs2 from Saccharomyces cerevisiae. (2025). Acta Cryst. F81, 365-373.
Cryo-EM structures of a MexB–MexY chimeric efflux pump reveal that large open clefts are intrinsic to the MexY porter domain. (2026). Acta Cryst. F82, 83-93.
Crystal structure of glutamyl-tRNA synthetase from Helicobacter pylori. (2024). Acta Cryst. F80, 335-340.
Cryo-EM structures of apo and atorvastatin-bound human 3-hydroxy-3-methylglutaryl-coenzyme A reductase. (2025). Acta Cryst. F81, 118-122.
Crystal structure of a seven-substitution mutant of hydroxynitrile lyase from rubber tree. (2025). Acta Cryst. F81, 398-405.
PERC: a suite of software tools for the curation of cryoEM data with application to simulation, modeling and machine learning. (2025). Acta Cryst. F81, 441-450.
Crystal structure of carbon–nitrogen hydrolase from Helicobacter pylori G27. (2026). Acta Cryst. F82, 66-74.
CryoCrane: an open-source GUI for analyzing cryo-EM screening data sets. (2025). Acta Cryst. F81, 62-65.
The structure of a pectin-active family 1 polysaccharide lyase from the marine bacterium Pseudoalteromonas fuliginea. (2024). Acta Cryst. F80, 142-147.
Crystal structure of N-terminally hexahistidine-tagged Onchocerca volvulus macrophage migration inhibitory factor-1. (2024). Acta Cryst. F80, 328-334.
Structures of Trichomonas vaginalis macrophage migratory inhibitory factor. (2024). Acta Cryst. F80, 341-347.
The structure of His15 acetamide-modified hen egg-white lysozyme: a nice surprise from an old friend. (2025). Acta Cryst. F81, 41-46.
Crystallographic fragment screen of the c-di-AMP-synthesizing enzyme CdaA from Bacillus subtilis. (2024). Acta Cryst. F80, 200-209.
Structures of Mycobacterium tuberculosis isoprenyl diphosphate synthase Rv2173 in substrate-bound forms. (2025). Acta Cryst. F81, 193-200.
Crystal structure of guanosine 5′-monophosphate synthetase from the thermophilic bacterium Thermus thermophilus HB8. (2024). Acta Cryst. F80, 278-285.
Crystal structure and functional characterization of an Asp49 phospholipase A2 from the bushmaster (Lachesis muta). (2026). Acta Cryst. F82, 150-159.
The first report of structural analysis of a nucleic acid using crystals grown in space. Corrigendum. (2025). Acta Cryst. F81, 177-178.
Crystal structure of Crocus vernus class IIIb chitinase: in silico ligand-binding studies and in vitro antifungal assay. (2026). Acta Cryst. F82, 14-22.
Crystal structures of Escherichia coli glucokinase acetylation-mimicking variants and insights into the impact of acetylation. (2026). Acta Cryst. F82, 160-166.
The structure of the Gemella haemolysans M26 IgA1 protease trypsin-like domain. (2025). Acta Cryst. F81, 124-129.
A first structural model for covalent dimerization of S100 proteins. (2026). Acta Cryst. F82, 176-183.
Automated gradient equilibration of macromolecular crystals to new solution conditions. (2025). Acta Cryst. F81, 478-486.
Structural analysis of YcdY, a member of the redox-enzyme maturation protein family. (2025). Acta Cryst. F81, 263-271.
Structural analysis of the tetrahydrobiopterin glucosyltransferase PsBGluT from Pseudanabaena sp. Chao 1811. (2025). Acta Cryst. F81, 495-504.
X-ray crystal structure of proliferating cell nuclear antigen 1 from Aeropyrum pernix. (2024). Acta Cryst. F80, 294-301.
Crystal structure of the plant GABA aminotransferase AtGABA-T from Arabidopsis thaliana. (2026). Acta Cryst. F82, 208-215.
Structural insights into the binding mode of the hypnotic drug vornorexant to orexin receptors. (2026). Acta Cryst. F82, 201-207.
Crystal structure of the virulence protein J (VirJ) domain 1 from Brucella abortus. (2025). Acta Cryst. F81, 374-380.
High-throughput protein crystallography to empower natural product-based drug discovery. (2025). Acta Cryst. F81, 179-192.
Crystal structures of the putative endoribonuclease L-PSP from Entamoeba histolytica. (2025). Acta Cryst. F81, 226-234.
Crystal structure analysis of oxygen-induced degradation occurring in rsCherry. (2025). Acta Cryst. F81, 311-318.
Enhancing the apo protein tyrosine phosphatase non-receptor type 2 crystal soaking strategy through inhibitor-accessible binding sites. (2024). Acta Cryst. F80, 210-219.
Crystal structure of Plasmodium vivax macrophage migration inhibitory factor. (2026). Acta Cryst. F82, 194-200.
Crystal structure of dihydroorotate dehydrogenase from Helicobacter pylori with bound flavin mononucleotide. (2025). Acta Cryst. F81, 108-117.
Crystallization and initial X-ray crystallographic analysis of a de novo-designed protein with left-handed βαβ units. (2025). Acta Cryst. F81, 216-220.
Structural insights into a fucosidase involved in fucoidan degradation. (2025). Acta Cryst. F81, 459-466.
Crystal engineering of the hepatoma-derived growth factor-related protein 2 PWWP domain towards crystallographic fragment screening. (2025). Acta Cryst. F81, 358-364.
Crystal structure of a recombinant Agaricus bisporus mushroom mannose-binding protein with a longer C-terminal region. (2025). Acta Cryst. F81, 241-248.
A new crystal form of the DNA-free full-length XPD helicase from Thermoplasma acidophilum. (2026). Acta Cryst. F82, 42-48.
Analysis of Burkholderia pseudomallei IspF in complex with sulfapyridine, sulfamonomethoxine, ethoxzolamide and acetazolamide. (2025). Acta Cryst. F81, 138-145.
Crystal structures of the 3C proteases from Coxsackievirus B3 and B4. (2024). Acta Cryst. F80, 183-190.
Crystal structure of the S-adenosylmethionine-dependent mycolic acid synthase UmaA from Mycobacterium tuberculosis. (2025). Acta Cryst. F81, 146-154.
Structure of an Fe2+-binding-deficient mimiviral collagen lysyl hydroxylase. (2025). Acta Cryst. F81, 235-240.

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