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Figure 5
Three model structures (models A–C) considered for reconstructions using xFrame: (a)–(d) a pentagonal cluster consisting of spheres of uniform density with a diameter of 140 nm, with the red spheres being of doubled density as compared with the blue spheres; (e)–(h) the human apoptosome (PDB entry 3j2t; Yuan et al., 2013BB86); (i)–(l) the mechano­sensitive ion channel Piezo1 (PDB entry 6b3r; Guo & MacKinnon, 2017BB30). The two upper rows show distinct views of the 3D structures. The third row displays 2D slices through the centers of the respective 3D models, and the bottom row displays 2D projections on the image plane, which were produced using the electron-density maps generated in UCSF Chimera (Pettersen et al., 2004BB67) for the corresponding 3D models. The white scale bars shown in the two bottom rows correspond to 5 nm.

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ISSN: 1600-5767
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