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Figure 1
(a) Elution profiles of the UV280, dRI, and SAXS I0, Rg and aggregation number N (= 4 for tetramer) of the native TTR over the SEC-SWAXS elution peak. The frame number corresponds to the SWAXS data collection interval (2 s per frame) which was initiated selectively, slightly ahead of the onset of the sample elution peak. (b) Global and (c) local comparisons of the SWAXS data (SASBDB entry code SASDXW3) with the calculated SWAXS profiles (with the χ2 shown) of the existing TTR crystal structures (PDB codes indicated) using CRYSOL (version 3.0). (d) and (e) Similar comparisons with the SWAXS profiles calculated using WAXSis. Arrows in (b), (c), (d) and (e) mark the regions of more prominent fitting deviations.

Journal logoJOURNAL OF
APPLIED
CRYSTALLOGRAPHY
ISSN: 1600-5767
Volume 58| Part 4| August 2025| Pages 1373-1383
https://doi.org/10.1107/S1600576725004716
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