view article
Figure 3
(a) NMR characterizations of tolcapone binding to TTR, with the residue-specific chemical shift changes Δδ of TTR on binding to tolcapone higher than the red dashed line (the mean value plus one standard deviation of Δδ). (b) Close-up view of the binding pocket T4 site showing the key hydrogen bonding amino acids involved in the coordination of tolcapone with TTR.

Journal logoJOURNAL OF
APPLIED
CRYSTALLOGRAPHY
ISSN: 1600-5767
Volume 58| Part 4| August 2025| Pages 1373-1383
https://doi.org/10.1107/S1600576725004716
Follow J. Appl. Cryst.
Sign up for e-alerts
E-alerts
Follow J. Appl. Cryst. on Twitter
Twitter
Follow us on facebook
Facebook
Sign up for RSS feeds
RSS