Figure 7
(a) Classification of primary sulfonamide synthons reported in CSD and (b) their hydrogen bonding and frequency. (c) Synthons in cocrystals of primary sulfonamides with N-oxides and amides. The latter analysis suggests that sulfonamide–N-oxide synthons may be replaced by syn-amides to give a new strategy for sulfonamide–carboxamide cocrystals. |