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Figure 6
Hydrogen-bonding synthons of ACZ observed in this study. (a) Molecular diagram showing the hydrogen bonding groups as rigid or flexible (according to Arenas-García et al., 2010BB5, 2012BB6). (b) Synthon 1 between the acetamide and thiadiazole ring of ACZ with carboxylic acid, carboxamide, syn-amide, respectively. (c) Synthon 2 between the sulfonamide group of ACZ and pyridine carboxamides, e.g. NAM, PAM, to give large ring motifs. (d) Synthon 3 connects sulfonamide, thiadiazole N and lactam conformer C. The graph-set notations of ring motifs are given for identification.

Volume 3| Part 2| March 2016| Pages 152-160
ISSN: 2052-2525