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Figure 1
Chip designs for the on-chip crystallization of proteins. (a) Roadrunner I chips have overall dimensions of 4.5 × 2.5 mm and up to 10 000 micro-pores, and are equipped with a standard magnetic base, making them compatible with data collection on most MX synchrotron beamlines. (b) Roadrunner II chips are much larger, with overall dimensions of 32 × 12 mm, and provide up to 300 000 micro-pores for crystals. They are glued onto an aluminium support frame (shown in light gray), which is mounted on a standard magnetic mount (shown in black). Room-temperature data collection with Roadrunner II chips requires a special scanning stage with a long travel range of more than 32 mm, such as the Roadrunner II goniometer (Tolstikova et al., 2019BB999). The so-called `humidor' (shown in green) can be slid over the chip to protect the crystals from drying out and from light exposure.

Volume 6| Part 4| July 2019| Pages 714-728
ISSN: 2052-2525