On-chip crystallization for serial crystallography experiments and on-chip ligand-binding studies

Lieske, J.; Cerv, M.; Kreida, S.; Komadina, D.; Fischer, J.; Barthelmess, M.; Fischer, P.; Pakendorf, T.; Yefanov, O.; Mariani, V.; Seine, T.; Ross, B.H.; Crosas, E.; Lorbeer, O.; Burkhardt, A.; Lane, T.J.; Guenther, S.; Bergtholdt, J.; Schoen, S.; Törnroth-Horsefield, S.; Chapman, H.N.; Meents, A.

doi:10.1107/S2052252519007395

Figure 9
Accumulated Bragg spots of 3000 patterns collected from hAQP2 crystals with the silicon chip oriented perpendicular to the beam (a) and at a tilt angle of 25° (b). The preferred orientation of the crystals lying on the silicon-chip surface leads to poor coverage of reciprocal space. In order to obtain a more complete data set, the chip has to be tilted during data collection. The color code of the scale bars indicates the number of patterns that contribute to each pixel in merged reciprocal space.

IUCrJ

Volume 6| Part 4| July 2019| Pages 714-728

ISSN: 2052-2525

https://doi.org/10.1107/S2052252519007395

BIOLOGY | MEDICINE

Open

access

Follow IUCrJ

Search IUCr Journals		doi		Advanced search
Author		volume	page