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Figure 1
Schematic diagram of the Complex-LCP method. After crystallization conditions have been identified and optimized, the target receptor is purified in complex with a transient ligand and screened against a panel of N ligands using nanolitre-volume high-throughput robotic crystallization in 96-well glass sandwich plates. Those ligands that support crystallization are then used to prepare samples for XFEL data collection in syringes.

Volume 6| Part 6| November 2019| Pages 1106-1119
ISSN: 2052-2525