Figure 3
Detailed view of the putative IdmH active site, highlighting key residues. The abundance of aromatic/hydrophobic residues in the active site might play a role in the catalysis of indane-ring formation by guiding the mainly hydrophobic substrate into an appropriate conformation for catalysis. The residues are coloured according to the normalized consensus hydrophobicity scale, where the most hydrophobic residues are red and the most hydrophilic residues are white (Eisenberg et al., 1984). |