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Figure 11
SAD ambiguity resolution from density modification. Examples are taken from the sulfur SAD analysis of DnaK–ATP (Liu et al., 2013BB125). (a) Phase probability distributions for a particular reflection as evaluated in Phaser from SAD combined with the S-atom partial structure (red) and after using DM for density modification that excluded molecular averaging. (b) A portion of the electron-density distribution phased from SAD combined with the sulfur partial structure. (c) The same portion of the map after density modification.

IUCrJ
Volume 10| Part 5| September 2023| Pages 521-543
ISSN: 2052-2525
https://doi.org/10.1107/S2052252523006449