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Figure 1
MR models and their corresponding structures for the small antiviral protein LCB2. (a)–(f) Superposition of the final structures (red) and their parent MR models (blue, annotated at the top of the panels). The structures are superimposed via Cα atoms from the first and second helices (residues 6–22 and 25–41). (g) Intermolecular hydrogen bond between residues Asn43 and Glu46 in the structure derived from the AlphaFold3 model (for visual clarity, we do not show the symmetry-equivalent hydrogen bond). (h) Superposition of the six crystallographic structures colored according to their parent MR models: blue (AlphaFold3), magenta (AlphaFold2), green (MultiFOLD), turquoise (Rosetta), red (RoseTTAFold) and orange (trRosetta). The structures are superimposed via Cα atoms from the consensus set. (i) Superposition of the six crystallographic structures with side chains colored according to their parent MR models. The structures are superimposed via Cα atoms from the consensus set, as in panel (h). The figures were prepared using the program CCP4MG (McNicholas et al., 2011BB57).

IUCrJ
Volume 12| Part 4| July 2025|
ISSN: 2052-2525
https://doi.org/10.1107/S2052252525005123