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Figure 3
Atomic models for C9 MACPF domain conformations present in the soluble crystal structure [PDB entry 6cxo, (a); Spicer et al., 2018View full citation], the inhibited sMAC [PDB entry 7nyd, (b); Menny et al., 2021View full citation] and the transmembrane pore [PDB entry 6h04, (c)]. Residues that undergo the helix-to-hairpin transition are coloured (TMH1, cyan; TMH2, pink).

IUCrJ
Volume 13| Part 3| May 2026| Pages 221-227
ISSN: 2052-2525