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Figure 2
(A) Plot of the change over time in the distribution of resolutions in deposited cryo-EM structures. (B) Schematic representation of the concept that there is a progressive increase in the amount of information that can be derived from cryo-EM maps as the resolution improves, with inflection points at selected resolutions where new structural features can be discerned: α-helices at 7 Å, β-strands at 4.5 Å, side chains at 3 Å, and water molecules and other high-resolution features at 2 Å and beyond.

ISSN: 2052-2525