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Figure 4
Comparison of ab initio 3D reconstructions. (a) 52 kDa streptavidin reconstructed using the method described in this study (left), volume-based probabilistic projection matching (middle) (Van et al., 2025View full citation) and a map refined in RELION for comparison (right). (b) Asymmetric export gate reconstructed using the method described in this study (left), volume-based probabilistic projection matching (middle) (Van et al., 2025View full citation) and an ab initio model generated with cryoSPARC for comparison (right). (c) Asymmetric main conformation of merozoite surface protein 1 reconstructed using the method described in this study (left), volume-based probabilistic projection matching (middle) (Van et al., 2025View full citation) and a map refined in cryoSPARC for comparison (right).

IUCrJ
Volume 13| Part 4| July 2026|
ISSN: 2052-2525
https://doi.org/10.1107/S2052252526003611