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Figure 3
(a) Sectioned surface-rendered models of baseplate and needle of ΦCD508 (right) and Av-CD291.2 (left). Analogous or homologous subunits are coloured the same in the two structures. (b) Low-pass filtered cryoEM reconstruction of ΦCD508 baseplate and terminal region of the tail. An atomic model of the baseplate hub, wedge and tail components is shown, highlighting the unfitted density corresponding to the attached tail fibres. (c) Overlay of ΦCD508 and Av-CD291.2 hub and needle indicating structural homology of needle proteins and core domains of the hub protein. The additional hub-hydrolase domains of Av-CD291.2 (pale blue) are seen radiating out from the central axis.

ISSN: 2052-2525