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Figure 6
Single-particle cryo-EM structures of aqua­glyceroporin TbAQP2. (a)–(c) Monomer conformations of TbAQP2, (a) free or in complex with (b) pentamidine or (c) melarsoprol, from extracellular and side views, highlighting the ar/R filter residues. Helices are partially removed in the side views for clarity. (d) Monomer conformation of TbAQP2 in complex with melarsoprol reported by Matusevicius et al. (2026View full citation). More detailed structural information is provided in Table 1[link].

IUCrJ
Volume 13| Part 4| July 2026|
ISSN: 2052-2525
https://doi.org/10.1107/S2052252526003234