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The following articles are a selection of those recently accepted for publication in IUCrJ.
See also Forthcoming articles in all IUCr journals.
topical reviewStructural biology in the time of COVID-19: perspectives on methods and milestones
The one-year anniversary of the declaration of the outbreak of SARS-CoV-2 as a pandemic, combined with the 50th anniversary of the PDB, provides a unique occasion to observe the role played by structural methods in the fight against COVID-19. A revealing portrait of the many contributions of the structural biology community is presented.
research papersPutative glycosyltransferase hexameric functional unit revealed by the crystal structure of Acinetobacter baumannii MurG
We characterized the MurG glycosyltransferase of the human pathogen Acinetobacter baumannii and unveiled its hexameric crystal structure. We believe that our study makes a significant contribution to the literature because this is the first homo-oligomeric structure among the MurG and Mur families of ligases to be described. Our study clarifies the homo-oligomerization mechanism of the MurG ligase, thus opening the door for designing next-generation antibiotics that target the MurG ligase.
research papersImproved grain mapping by laboratory X-ray diffraction contrast tomography
The present laboratory diffraction contrast tomography suffers from poor spatial resolution – only grains larger than 40 µm can be reliably imaged. In this work we show how this serious limitation can be lifted and the spatial resolution improved significantly.
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