forthcoming articles

Single-particle cryo-EM will soon equal the number of yearly entries in the Protein Data Bank from structures determined by X-ray crystallography. Considering the growing outreach of cryo-EM, it is timely to remind users of and define typical terms important for understanding the underlying fundamental physical concepts and key basics of single-particle cryo-EM and image processing, which are particularly relevant for the expanding cryo-EM community, including for newcomers and scientists joining from related fields.

A novel vacuum-compatible liquid sheet jet nozzle, utilizing a second gas sheath, successfully generates stable aqueous films under 100 nm in thickness, overcoming previous freezing limitations in vacuum environments. This development simplifies operations and is demonstrated to be viable for high-repetition-rate X-ray scattering measurements at X-ray free-electron laser sources, broadening the applications for studying matter in solution.

This review summarizes recent experimental and theoretical advances in the magnetism of quasicrystals and their approximant crystals, and formulates three complementary and hierarchical design principles – valence electron concentration, crystal electric field-induced anisotropy and structural control of magnetic frustration – as primary tools for systematically tuning the magnetic ground states in these compounds.

Post-acquisition super resolution (PASR) is a pre-processing step which can be utilized to exceed the resolution limit of already-acquired data if the limit is reached. It is designed to be as minimally invasive to all general single particle workflows as possible, allowing users to choose which suite they prefer.