Direct phase determination for macromolecular crystals using the multiple-diffraction technique and an in-house X-ray source

This paper reports the first attempt at using a rotating-anode X-ray source and the multibeam diffraction technique to determine the phases of X-ray reflections from macromolecular crystals. Invariant phases of structure-factor triplets of lysozyme are determined unambiguously via four-beam diffractions.