journal menuBuy article online - an online subscription or single-article purchase is required to access this article.
research papers
An efficient algorithm is described for finding the maximum entropy density distribution under the constraint that (Σ |F|cos (2πh . r- φ)), where the sum is over a subset of reflections whose phase has been determined, is constant. This algorithm is combined with solvent flattening in a procedure for extending phases to higher resolution. A test of the procedure on the structure of ribonuclease A and its application to the determination of two previously unknown structures are discussed.
Subscribe to Acta Crystallographica Section A: Foundations and Advances
