(−)-(R)-5,5-Dimethylmorpholinyl-2-acetic Acid Ethyl Ester Hydrochloride, C10H20NO3+.Cl−

Frydenvang, K.; Enna, S.J.; Krogsgaard-Larsen, P.

doi:10.1107/S0108270197004290

(-)-(R)-5,5-Dimethylmorpholinyl-2-acetic Acid Ethyl Ester Hydrochloride, C₁₀H₂₀NO₃⁺.Cl^-

K. Frydenvang, S. J. Enna and P. Krogsgaard-Larsen

One of the enantiomers of 5,5-dimethylmorpholinyl-2-acetic acid is observed to be a GABA_B receptor antagonist. The absolute configuration of the inactive enantiomer is found to be the (R) configuration. The morpholine ring adopts a chair conformation with the acetic acid moiety in an equatorial position. In the crystal packing hydrogen bonds are observed between the ammonium group and the chloride ions.

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(-)-(R)-5,5-Dimethylmorpholinyl-2-acetic Acid Ethyl Ester Hydrochloride, C₁₀H₂₀NO₃⁺.Cl^-

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	Crystallographic Information File (CIF) Contains datablocks sch50910, global
	Structure factor file (CIF format) Contains datablock sch50910

(-)-(R)-5,5-Dimethylmorpholinyl-2-acetic Acid Ethyl Ester Hydrochloride, C10H20NO3+.Cl-

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(-)-(R)-5,5-Dimethylmorpholinyl-2-acetic Acid Ethyl Ester Hydrochloride, C₁₀H₂₀NO₃⁺.Cl^-