Figure 4
The reconstructed HbGp globin chains based on the molecular replacement solution using a protomer of HbLt as the search model. The structure shows the offset of the vertices of the upper disc with respect to the lower one, characteristic of the type I architecture. This is most evident towards the centre of the structure where subunits from the two layers can be clearly visualized. HbLt is shown for comparison. In both images red refers to subunits of the upper disc whilst green (or blue) refer to those of the lower disc. |