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Figure 2
The 28 mm-thick specimen A with mixed ductal-lobular carcinoma. (a) Mammogram of the specimen (26 kVp, 8.0 mAs). Note the flabellate connective tissue septa between the arrows, highly suggestive of cancer. (b) CT image of the specimen (80 kVp, 50 mAs). Collagen septa among the adipose tissue are seen (arrowheads). (c) MR image of the specimen (T1, spin echo, TR = 400 ms, TE = 15 ms, NEX = 8). The arrowheads are as in (b). (d) ABI-CT peak image of the same cross section (33 keV). Pleomorphic calcifications (arrowheads) with irregular margins, and a presumable focus of the tumour (arrow) are seen. (e) ABI-CT slope image of the same cross section (33 keV). The arrow and arrowheads are as in (d). (f) Scanner image of the corresponding histological whole-mount slide (Herovici's stain; original magnification, ×1). Calcifications (black arrowheads), invasion of ductal carcinoma (black arrows), lobular carcinoma in situ and atypical hyperplasia (grey arrow), and high-density partially wavy and braided connective tissue (grey arrowhead) are seen with a microscope. The nuclei are shown in brown or black, mature collagen in red and adipocytes in white. At this magnification the individual carcinoma cells are not visible.

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SYNCHROTRON
RADIATION
ISSN: 1600-5775
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