Figure 3
The 11 mm-thick specimen B with lobular carcinoma. (a) Mammogram of the specimen (26 kVp, 2.2 mAs). Note two benign calcifications (arrows). (b) CT image of the specimen (80 kVp, 50 mAs). Strands of connective tissue (arrowheads) are barely seen. (c) MR image of the specimen (T1, spin echo, TR = 400 ms, TE = 15 ms, NEX = 8). Some suspect areas (arrows) are seen. (d) ABI-CT peak image of the same cross section (33 keV). Presumed foci of the tumour and morphological changes (arrowheads) are visible. (e) ABI-CT slope image of the same cross section (33 keV). Some strands penetrating to adipose tissue (arrowheads) are seen. (f) Scanner image of the corresponding histological whole-mount slide (Herovici's stain; original magnification, ×1). An `Indian file' growth pattern (black arrowheads), targetoidal arrangement (black frames), and a combination of these two patterns (grey arrow) can be seen with a microscope. An ILC (solid black arrows), periductal invasion (between the dashed lines), vascular invasion (grey frame) and some cystic changes next to the large circular duct (dashed black arrow) are also seen with a microscope. |